Fibromyalgia and Laboratory Tests

There are no known routine laboratory tests that are useful in the evaluation or monitoring of FMS. The diagnosis is based on the clinical features and is not one of exclusion. Nevertheless, depending on the presentation, a number of simple laboratory investigations may be ordered if it is thought that the FMS is occurring in conjunction with another condition. The complete blood count, erythrocyte sedimentation rate, thyroid function tests, muscle enzymes, antinuclear antibody, and rheumatoid factor together with a biochemical screen, may be deemed appropriate. In patients with localized fibromyalgia with a history of injury, imaging of spinal regions may be needed to assess the anatomic status of central paraspinal structures. The choice of imaging technique depends on the clinical situation and the severity of the FMS and the presence of any other signs that do not fit with FMS.

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